“Dense binding in the basal ganglia and cerebellum suggests cannabinoid involvement in movement control . . . Anticonvulsant and antiemetic effects of cannabinoids have therapeutic value. The localization of cannabinoid receptors in motor areas suggests additional therapeutic applications. Cannabinoids exacerbate hypokinesiain Parkinson disease but are beneficial for some forms of dystonia, tremor, and spasticity.”
Herkenham, M., Lynn, A.B., et al., (1990) “Cannabinoid Receptor Localization in Brain,” Proceedings of the National Academy of Sciences, 87:1932-1936, 1990. pg. 1936.