Basic research on rewarding, tolerance and
In recent years, scientists were able to show that
animals do self-administer THC under certain conditions.
Basic animal research also shows that cannabis produces
tolerance and withdrawal. This research helps explain
abuse of cannabis and dependency in humans. However,
basic research cannot predict how pronounced these effects
will be in humans and whether they are stronger or less
strong compared to other drugs such as caffeine, nicotine
and heroin. More...
Dependency compared to other drugs
Compared to other widely used drugs (alcohol, tobacco,
opiates) a smaller percentage of cannabis users become
dependent. Dependency is also less severe compared to
many other legal and illegal drugs. The relatively low
dependence liability of cannabis is widely recognized.